Search engine run on: http://www.csse.monash.edu.au/
Glookbib search for: MolBio alignment LAllison
%A J. Collier
%A L. Allison
%A A. Lesk
%A M. Garcia de La Banda
%A A. Konagurthu
%T A new statistical framework to assess structural alignment quality using
information compression
%J ECCB
%W Strasbourg
%M SEP
%D 2014
%K conf, ECCB 14, MolBio, c2014, c201x, c20xx, zz0914, LAllison, ArunK, AMLesk,
protein, 3D, similar, structure, alignment, match, MML, MDL, AIC, complexity,
bioinformatics, 13th European Conference on Computational Biology,
I value, Ivalue,
%X "... proposes a new statistical framework to assess structural alignment
quality and significance based on lossless information compression. This is
a radical departure from the traditional approach of formulating scoring
functions. It links the structural alignment problem to the general class of
statistical inductive inference problems, solved using the
information-theoretic criterion of minimum message length. Based on this, we
developed an efficient and reliable measure of structural alignment quality,
I-value. The performance of I-value is demonstrated in comparison with a
number of popular scoring functions, on a large collection of competing
alignments. Our analysis shows that I-value provides a rigorous and reliable
quantification of structural alignment quality, addressing a major gap in
the field."
-- [doi:10.1093/bioinformatics/btu460],
[more].
%A M. D. Cao
%A T. I. Dix
%A L. Allison
%T A genome alignment algorithm based on compression
%J BMC Bioinformatics
%V 11
%N 1
%P 599
%M DEC
%D 2010
%K jrnl, eJrnl, MolBio, c2010, c201x, c20xx, Minh Duc Cao, LAllison, TIDix,
highly accessed paper, DNA, whole genome alignment, zz0111, local alignment,
sequence, long, compress, compression, poa, XM, expert model, XMAligner
%X "... Since genomic sequences carry genetic info., this article proposes that
the info. content of each nucleotide in a posn should be considered in
sequence alignment. An info.-theoretic approach for pairwise genome local
alignment, namely XMAligner, is presented. Instead of comparing sequences at
the character level, XMAligner considers a pair of nucleotides from two
seqs. to be related if their mutual info. in context is significant. The
info.content of nucleotides in sequences is measured by a lossless
compression technique. ... Experiments on both simulated data & real data
show that XMAligner is superior to conventional methods especially on
distantly related seqs. & statistically biased data. XMAligner can align
seqs. of eukaryote genome size with only a modest hardware requirement. ..."
-- [more],
-- [doi:10.1186/1471-2105-11-599][12/'10] (BMC 17/2/12 mail: 3372 accesses),
-- 21159205@[pubmed][2/'11].
%A A. Konagurthu
%A L. Allison
%A T. Conway
%A B. Beresford-Smith
%A J. Zobel
%T Design of an efficient out-of-core read alignment algorithm
%J WABI
%I SpringerVerlag
%S LNCS/LNBI
%V 6293
%P 189-201
%M SEP
%D 2010
%K wShop, MolBio, c2010, c201x, c20xx, zz1010, WABI, WABI10, nicta, LAllison,
Syzygy, ArunK, Algorithms in Bioinformatics, short read, reads, NGS, align,
mapping, next generation, DNA, sequencing, algorithm
%X "New genome sequencing technologies are poised to enter the sequencing
landscape with significantly higher throughput of read data produced at
unprecedented speeds & lower costs per run. However, current in-memory
methods to align a set of reads to one or more reference genomes are
ill-equipped to handle the expected growth of read-throughput from newer
technologies. ... reports the design of a new out-of-core read mapping alg.,
Syzygy, which can scale to large volumes of read & genome data. The alg. is
designed to run in a constant, user-stipulated amount of main memory -
small enough to fit on standard desktops - irrespective of the sizes of read
& genome data. Syzygy achieves a superior spatial locality-of-reference that
allows all large data structures used in the alg. to be maintained on disk.
We compare our prototype implementation with several popular read alignment
programs. Our results demonstrate clearly that Syzygy can scale to very
large read volumes while using only a fraction of memory in comparison,
without sacrificing performance."
-- [more],
-- [doi:10.1007/978-3-642-15294-8_16]['10].
(In: uk us isbn:3642152937; uk us isbn13:978-3-642-15293-1.)
%A M. D. Cao
%A T. I. Dix
%A L. Allison
%T Computing substitution matrices for genomic comparative analysis
%J Advances in Knowledge Discovery and Data Mining
%I SpringerVerlag
%S LNCS
%V 5476 / 2009
%P 647-655
%M APR
%D 2009
%K conf, PAKDD, MolBio, c2009, c200x, c20xx, zz0509, bioinformatics, PAKDD09,
PAKDD13, DNA, genome, comparative analysis, comparison, substitution matrix,
PAM, blosum, estimation, alignment, free, homology, MML, MDL, information,
XM, Minh Duc Cao, TIDix, LAllison, (NICTA), malaria genome
%X "Substitution matrices ... and are important for many knowledge discovery
tasks such as phylogenetic analysis and sequence alignment. ... present a
novel algorithm that addresses this by computing a nucleotide substitution
matrix specifically for the two genomes being aligned. ... uses compression
... reconstructs, with high accuracy, the substitution matrix for
synthesised data generated from a known matrix with introduced noise. ...
successfully applied to real data for various malaria parasite genomes,
which have differing phylogenetic distances and composition that lessens the
effectiveness of standard statistical analysis techniques."
pdf@[doi:10.1007/978-3-642-01307-2_64]['09], and
[substitution matrices].
%A M. D. Cao
%A T. I Dix
%A L. Allison
%T A genome alignment algorithm based on compression
%R 2009/233
%I Faculty of Info. Tech. (Clayton), Monash University
%M JAN
%D 2009
%K TR, TR233, MolBio, c2009, c200x, c20xx, bioinformatics, zz0109, FIT, Monash,
Minh Duc Cao, TIDix, LAllison, data, DNA, sequence, compression, compressed,
compress, align, strings, information, content, free, XM, XMAligner
%X "Traditional genome alignment methods based on dynamic programming are often
a. computational expensive, b. unable to compare the genomes of distant
species, & c. unable to deal with low information regions. ... information-
-theoretic approach for pairwise genome local alignment. ... the expert model
aligner, the XMAligner, relies on the expert model compression alg.. To align
2 seqs., XMAligner 1st compresses one sequence to measure the info. content
at each posn in the seq.. Then the seq. is compressed again but this time
with the background knowledge from the other seq. to obtain the conditional
info. content. The info. content & the conditional info. content from the
2 compressions are examined. Similar regions in the compressed seq. should
have the conditional info. content lower than the individual info. content.
... applied to align the genomes of Plasmodium falciparum & P. knowlesi v.
other 3 P. genomes with different levels of diversity. Despite the
differences in nucleotide composition of the reference seqs., the conserved
regions found by XMAligner in 3 alignments are relatively consistent. A
strong correlation was found between the similar regions detected by the
XMAligner & the hypothetical annotation of Plasmodium species. The alignment
results can be integrated into the DNAPlatform for visualisation."
-- [abs]['09].
[Also search for: Cao Dix Allison Bioinformatics c2010],
and see [compression]['09].
%A D. R. Powell
%A L. Allison
%A T. I. Dix
%T Modelling alignment for non-random sequences
%J Advances in Artificial Intelligence
%I SpringerVerlag
%S LNCS/LNAI
%V 3339
%P 203-214
%M DEC
%D 2004
%O (17th ACS Australian Joint Conf. on Artificial Intelligence, AI2004)
%K conf, AI, MolBio, dynamic programming algorithms, DPA, c2004, c200x, c20xx,
similar, sequence, homology, Malignment, minimum message length, MML, MDL,
PRSS, FASTA, BLAST, Smith Waterman, context, significance test, P values,
Pvalue, DNA, dependent, low information content, score, pattern, repeats,
repetitive, shuffling, masking, scoring, quality, Markov, model, models,
hidden, HMM, PHMM, description, pair, strings, DRPowell, LAllison, TIDix,
bioinformatics
%X "Populations of biased, non-random seqs. may cause standard alignment
algorithms to yield false-positive matches & false-negative misses. A std
significance test based on the shuffling of sequences is a partial solutions
applicable to pop'ns that can be described by simple models. Masking-out
low information content intervals throws information away. ... new & general
method, modelling alignment: Population models are incorporated into the
alignment process, which can (& should) lead to changes in the rank-order of
matches between a query seq. & a collection of seqs., compared to results
from std algorithms. The new method is general & places very few conditions
on the nature of the models that can be used with it. We apply modelling-
alignment to local alignment, global alignment, optimal alignment & the
relatedness problem. Results: As expected, modelling-alignment & the
standard PRSS program from the FASTA package have similar accuracy on
sequence populations that can be described by simple models, e.g. 0-order
Markov models. However, modelling-alignment has higher accuracy on popns that
are mixed or that are described by higher-order models: It gives fewer false
positives & false negatives as show by ROC curves & other results from tests
on real and artificial data". isbn:3540240594.
-- [mAlign] inc software,
[doi:10.1007/978-3-540-30549-1_19]['11],
[pp.pdf][11/'04],
[also search for: Allison COMPJ c1999].
%A D. R. Powell
%A L. Allison
%A T. I. Dix
%T Fast, optimal alignment of three sequences using linear gap costs
%J J. Theor. Biol.
%V 207
%N 3
%P 325-336
%M DEC
%D 2000
%K jrnl, JTB, MolBio, Biology, multiple, sequence, alignments, similarity,
affine, linear, cost, gaps, insert, delete, indel, indels, DNA, time, speed,
fast, string, strings, iterative, phylogenetic, family tree, Ukkonen,
edit distance, dynamic programming algorithm, DPA, DRPowell, LAllison, TIDix,
c2000, c200x, c20xx, zz1100, J Theoretical Biology, bioinformatics
%X [...] The obvious dynamic programming algorithm for optimally
aligning k sequences of length n runs in O(n^k) time. This is
impractical if k >= 3 and n is of any reasonable length.
[...] new algorithm [is] guaranteed to find the optimal alignment [...]
particularly fast when the (three-way) edit distance is small. [...]
O(n + d^3) on average.
[paper][11/'00] and code,
[doi:10.1006/jtbi.2000.2177]['04]
more on [bioinformatics].
%A L. Allison
%A D. Powell
%A T. I. Dix
%T Modelling is more versatile than shuffling
%R 2000/83
%I School of Computer Science and Software Engineering, Monash University,
Australia 3168
%D 2000
%K MolBio, pair, two, sequence, alignment, PFSA, hidden Markov model, PHMM,
low medium information content, repeat, repetition, structure, pattern,
model, shuffle, shuffling, randomize, DNA, permute, tuples, frequencies,
family, PFSM, HMM, dynamic programming algorithm, DPA, homology, algorithm,
minimum message length, MML, description, MDL, LAllison, DRPowell, TIDix,
mAlignment, TR 83, TR83, c2000, c200x, c20xx, bioinformatics
%X It is shown how to incorporate almost any (left to right) model of a
population of sequences into the alignment DPA. Doing so is an alternative
to shuffling/ randomizing (Fitsch; Altschul, Erickson ...) the sequences
to correct for population biases. The resulting algorithm gives
fewer false positives, fewer false negatives, and can (and should)
change the rank ordering of alignments.
[also search for: modelling alignment]
[more],
[mon], and
[Bioinformatics].
%A D. R. Powell
%A L. Allison
%A T. I. Dix
%T A versatile divide and conquer technique for optimal string alignment
%J IPL
%V 70
%N 3
%P 127-139
%D 1999
%K IPL, jrnl, c1999, c199x, c19xx, zz0899, dynamic programming algorithm, DPA,
MolBio, DRPowell, LAllison, TIDix, bioinformatics, space, complexity,
strings, Edit Distance, similarity, LCS, Fast, Hirschberg, Ukkonen, Myers,
time, speed, Linear Space, Check Point, pointing, checkpoint, algorithms
%X A check-pointing (CP) technique uses O(n) space but is simpler
than Hirschberg's O(n)-space technique; H' ('97) attributes
an O(N**2)-time simple edit-distance CP to Eppstein. Here, CP
is applied to more complex cost functions, e.g., linear gap costs, and ...
to Ukkonen's O(n*d)-time DPA, even including linear gap costs,
to give O(n)-space, O(n.log d + d**2)-average-time,
effectively O(d**2)-time in many practical situations.
-- [doi:10.1016/S0020-0190(99)00053-8][6/'04],
& [Divide-and-C.].
%A L. Allison
%A D. Powell
%A T. I. Dix
%T Compression and approximate matching
%J COMPJ
%V 42
%N 1
%P 1-10
%D 1999
%K jrnl, MolBio, COMPJ, Computer Journal, LAllison, DRPowell, TIDix, pair,
string, strings, sequence, alignment, analysis, algorithm, homology,
similarity, limits, HMM, MML, MDL, II, normalized, limit, significance test,
testing, jie, med, DPA, low information content, repeats, repetitive, wei,
non-random, nonrandom, compressible, bioinformatics, pair, probabilistic,
information theory, features, complexity, time, fast, speed, shuffling,
shuffle, randomize, DNA, edit distance, hidden Markov model, HMM, PHMM,
c19xx, c1999, c199x, modelling, Malignment, context dependent, scoring
%X A population of sequences is called non-random if there is a statistical
model and an associated compression algorithm that allows members of the
population to be compressed, on average. Any available statistical model
of a population should be incorporated into algorithms for alignment of
the sequences and doing so changes the rank-order of possible alignments
in general. The model should also be used in deciding if a resulting
approximate match between two sequences is significant or not. It is
shown how to do this for two plausible interpretations involving pairs
of sequences that might or might not be related. Efficient alignment
algorithms are described for quite general statistical models of sequences.
The new alignment algorithms are more sensitive to what might be termed
`features' of the sequences. A natural significance test is shown to be
rarely fooled by apparent similarities between two sequences that are merely
typical of all or most members of the population, even unrelated members.
-- [more],
[doi:10.1093/comjnl/42.1.1]['06],
[pdf@compj]['05].
Also see [Powell AI2004],
and [bioinformatics].
%A L. Allison
%T Information-theoretic sequence alignment
%I School of Computer Science and Software Engineering, Monash University
%R 98/14
%M JUN
%D 1998
%K TR14, TR 14, MolBio, LAllison, string, strings, similarity, edit-distance,
homology, approximate match, matching, DNA, DPA, hidden Markov model, HMM,
low information content, repeats, repetitive, compressible, MML, MDL,
data compression, content, sequences, c1998, c199x, c19xx, bioinformatics
%X [TR98/14],
[TR98/14].
Also see: Allison, Powell and Dix, `Compression and Approximate Matching',
Comp. J. 42(1) pp1-10, 1999, for a fuller explanation and later results.
Also see [Bioinformatics].
%A D. R. Powell
%A L. Allison
%A T. I. Dix
%A D. L. Dowe
%T Alignment of low information sequences
%J Australian Computer Science Theory Symposium, CATS '98
%W Perth
%P 215-230
%I NUS
%M FEB
%D 1998
%K conf, MolBio, align, HMM, DPA, DNA, ACSC, CATS, CATS98, LAllison, DLDowe,
bioinformatics, probability, features, TIDix, Monash, c1998, c199x, c19xx,
DRPowell
%X [paper.ps]['98],
[more], uk us isbn:9813083921.
(Also see [Bioinformatics].)
%A L. Allison
%T Towards modelling evolution = mutation modulo selection in sequence
alignment
%R 95/225
%I Dept. Computer Science, Monash University
%M JUN
%D 1995
%K LAllison, Monash, TR225, TR 225, MolBio, evolution, pressure, selection,
fit, fitness, family, phylogenetic, evolutionary tree, trees, sequence,
multiple alignment, zz0795, c1995, c199x, c19xx, bioinformatics
%X [bioinformatics].
%A L. Allison
%T Using Hirschberg's algorithm to generate random alignments of strings
%J IPL
%V 51
%N 5
%P 251-255
%M SEP
%D 1994
%K c1994, c199x, c19xx, LAllison, Monash, jrnl, IPL, MolBio, bioinformatics, GS,
DNA, methods, MML, minimum message length encoding, II, inductive inference,
Hirschberg, string, sequence, alignment, similarity, homology, approximate,
match, matching, LCS, LCSS, edit distance, Bayesian, Gibbs sampling, MCMC,
random, sample, DPA, simulated annealing, SA, dynamic programming algorithm,
divide and conquer, hidden Markov model, HMM, probability,
posterior distribution, stochastic
%X Hirschberg's (CACM '75) recursive divide and conquer technique for
the dynamic programming technique (LCS, LCSS, Edit Distance) is
applied to the problem of sampling alignments of two strings
at RANDOM from the alignments' posterior probability distribution.
[more],
[reprint.ps],
[doi:10.1016/0020-0190(94)90004-3]['04].
Also see [Bioinformatics].
%A L. Allison
%A C. S. Wallace
%T An information measure for the string to string correction problem with
applications
%J 17th Australian Comp. Sci. Conf.
%P 659-668
%M JAN
%D 1994
%W Christchurch, N. Z.
%K LAllison, CSW, CSWallace, Monash, conf, MolBio, inductive inference, II,
string, sequence, family, evolutionary, phylogenetic, tree, trees,
variation, variance, uncertainty, estimate, estimation, parameters, DNA,
multiple alignment, Gibbs sampling, sample, GS, simulated annealing SA,
minimum message length MML, Bayesian, temperature, cooling, probabilistic,
NZ, New Zealand, c1994, c199x, c19xx, ACSC 17, 94, ACSC17, ACSC94,
bioinformatics, Monash
%O Australian Comp. Sci. Comm., Vol 16, No 1(C), 1994, isbn:047302313X.
%X It has been shown how to calculate a probability for an alignment.
Alignments are sampled from their posterior probability distribution.
This is extended to multiple alignments (of several strings). Averaging
over many such alignments gives good estimates of how closely the strings
are related and in what way. In addition, sampling in an increasingly
selective way gives a simulated annealing search for an optimal alignment.
[paper],
[Bioinformatics].
See also the related paper J. Mol. Evol. (39, pp418-430, 1994),
"The posterior probability distribution ...", for more results.
%A L. Allison
%A C. S. Wallace
%T The posterior probability distribution of alignments and its application
to parameter estimation of evolutionary trees and to optimization of
multiple alignments
%J J. Mol. Evol.
%V 39
%N 4
%P 418-430
%M OCT
%D 1994
%O An earlier version is TR 93/188, Dept. Comp. Sci., Monash U., July '93
%K jrnl, MolBio, JME, c1994, c199x, c19xx, LAllison, CSWallace, CSW, DNA,
bioinformatics, optimisation, estimate, infer, parameters, algorithm,
multiple, alignment, data, string, molecular, sequence, homology, Markov,
family, phylogenetic, tree, trees, edit distance, Monte Carlo method, mcmc,
simulated annealing, SA, inductive inference, II, sample, speed, Bayesian,
dynamic programming algorithm, DPA, stochastic, methods, GS, Gibbs sampling,
minimum message length encoding, MML, chain, minimum description length, MDL,
transthyretin, chloramphenicol resistance gene, CAT, CATB, CATD, CATP, CATQ,
CCOLI, ECOLI, algorithmic, mutual information, theory, significance,
probabilistic, temperature, limits, TR 93/188, TR188
%X "It is shown how to sample alignments from their posterior probability
distribution given two strings. This is extended to sampling alignments of
more than two strings. The result is firstly applied to the estimation of
the edges of a given evolutionary tree over several strings. Secondly,
when used in conjunction with simulated annealing, it gives a stochastic
search method for an optimal multiple alignment."
-- [paper] and source code,
[reprint.ps],
[doi:/10.1007/BF00160274]['07].
(The JME paper is a much expanded and changed version of TR 93/188,
[TR93/188](.ps))
%A L. Allison
%T A fast algorithm for the optimal alignment of three strings
%J J. Theor. Biol.
%V 164
%N 2
%P 261-269
%M SEP
%D 1993
%O TR 92/168 Dept. Computer Science, Monash University, Oct '92.
%K LAllison, Monash, jrnl, II, JTB, MolBio, bioinformatics, multiple alignment,
edit distance, Ukkonen, three, string, strings, sequence, sequences,
dynamic programming algorithm, DPA, TR 92 168 TR92-168 TR168,
c1993, c199x, c19xx, J Theoretical Biology
%X Given 3 strings, length ~ n, 3-way edit-distance d,
O(n.d^2) time algorithm worst case, O(n+d^3) typically.
Tree costs 0/1/2. ie. xxx :0; xxy, xx-, x-- :1; xyz, xy- :2
NB. Each internal node of an unrooted binary tree has 3 neighbours.
[more],
[reprint.ps],
[paper] inc' pdf paper and code,
[doi:10.1006/jtbi.1993.1153]['04],
and more on [bioinformatics].
%A L. Allison
%T Normalisation of affine gap costs used in optimal sequence alignment
%J J. Theor. Biol.
%M MAR
%D 1993
%V 161
%N 2
%P 263-269
%K LAllison, Monash, jrnl, MolBio, JTB, alignment, string, sequence analysis,
edit distance, homology, gap, gaps, linear, indel, insert delete, Altschul,
mutual information, similarity, hidden Markov model, HMM, bioinformatics,
inductive inference, II, c1993, c199x, c19xx, J Theoretical Biology
%X [more],
[reprint.ps],
[paper] inc' pdf.
%A L. Allison
%T Lazy dynamic programming can be eager
%J IPL
%V 43
%N 4
%P 207-212
%M SEP
%D 1992
%K LAllison, Monash, jrnl, FP, lazy functional programming, fast, efficient,
dynamic programming algorithm, DPA, edit distance, LCS, LCSS, MolBio,
approximate, similar, string strings, match, matching, sequence,
alignment, c1992, c199x, c19xx, bioinformatics
%X Lazy evaluation in a functional language is exploited to make the simple
dynamic programming algorithm for the edit-distance problem run quickly
on similar strings: being lazy can be fast.
Runs in O(n*d) time thanks to laziness.
[more],
[reprint.ps]
[html]
[doi:10.1016/0020-0190(92)90202-7]['07].
%A C. N. Yee
%A L. Allison
%T Fast string alignment with linear indel costs
%R TR 92/165
%I Computer Science, Monash University
%M JUL
%D 1992
%K LAllison, MolBio, string alignment, similarity, homology, Ukkonen,
edit distance, linear indel gap cost, costs, Ukkonen, Monash,
TR 165, TR92/165, TR165, II, c1992, c199x, c19xx, bioinformatics
%X two strings, O(n*d) time.
The constants in the cost function have to be "small" integers.
[Computing for Molecular Biology].
[Also search for: Ukkonen].
%A C. N. Yee
%A L. Allison
%T Reconstruction of strings past
%J Comp. Appl. BioSci. (J. Bioinformatics)
%V 9
%N 1
%P 1-7
%M FEB
%D 1993
%O TR 92/162, Dept. Computer Science, Monash University, May '92
%K LAllison, Monash, jrnl, MML, minimum message length, J. Bioinformatics,
encoding, hidden Markov model, HMM, II, inductive inference,
MolBio, string, sequence, alignment, homology, similarity, edit,
evolutionary, distance, parameter estimation, r-theory,
TR TR92-162 TR162 162, c1993, c199x, c19xx, CABIOS, J. Bioinformatics
%X Use of single optimal alignment gives biased estimates of the evolutionary
"distance" between two strings but the r-theory, average all alignments,
recovers accurate estimates over a very wide range of similarity.
-- [more],
[doi:10.1093/bioinformatics/9.1.1]['11],
[reprint.ps]
[paper.html].
Also see [Bioinformatics].
[now J. Bioinformatics].
%A L. Allison
%T Some algorithmic attacks on multiple alignment (abstract)
%J Boden Conf.
%W Thredbo, Australia
%M FEB
%D 1993
%K LAllison, Monash, RSBS, ANU, conf, MolBio, MML, II, string,
sequence, approximate match, matching, three, DPA, bioinformatics
%X also see [Bioinformatics].
%A L. Allison
%T Estimating parameters and evolutionary distances in the inference of
evolutionary trees (abstract)
%J Robertson Symposium.
%W Australian National University
%M JAN
%D 1993
%K LAllison, Monash, RSBS, ANU, conf, MolBio, MML, inductive inference,
II, string, sequence, multiple alignment, approximate match,
matching, phylogenetic, tree, trees, c1993, c199x, c19xx, bioinformatics
%X also see [Bioinformatics].
%A L. Allison
%A C. S. Wallace
%A C. N. Yee
%T Minimum message length encoding, evolutionary trees and multiple alignment
%J 25th Hawaii Int. Conf. on Sys. Sci.
%K LAllison, CSW, Monash, conf, MolBio, minimum message length encoding, MML,
ML, evolutionary, family, phylogenetic, tree, trees, CSWallace, CSW, human,
Bayesian, finite state, model, machine, FSM, hidden Markov model, primate,
HMM, DNA, multiple alignment, inductive inference, II, bioinformatics, chimp,
HICSS, HICSS25, HICCS92, TR 91 155, TR91-155, TR155, c1992, c199x, c19xx
%V 1
%P 663-674
%M JAN
%D 1992
%O TR 91/155, Dept. Computer Science, Monash University '91
%X "A method of Bayesian inference known as MML encoding is applied to inference
of an evolutionary tree and to multiple alignment for K >= 2 strings.
It allows the posterior odds-ratio of two competing hypotheses, for
example two trees, to be calculated. A tree that is a good hypothesis forms
the basis of a short message describing the strings. The mutation
process is modelled by finite-state machine. It is seen that tree
inference and multiple alignment are intimately connected."
-- [paper],
there is an example on the primate globin pseudo-genes.
(Also see [Bioinformatics].)
%A L. Allison
%A Du Xiaofeng
%T Relating three strings by minimum message length encoding (abstract)
%P 13
%J International Conference on Genes, Proteins and Computers
%W Chester
%I SERC Daresbury Laboratory
%M APR
%D 1990
%K LAllison, Monash, conf, MolBio, multiple, three, triple, alignment,
LCS, LCSS, MML, family, evolutionary phylogenetic tree, bioinformatics,
inductive inference, II, DNA, c1990, c199x, c19xx
%X also see [Bioinformatics].
%A L. Allison
%A C. S. Wallace
%A C. N. Yee
%T Finite-state models in the alignment of macro-molecules
%J J. Mol. Evol.
%V 35
%N 1
%P 77-89
%M JUL
%D 1992
%K LAllison, jrnl, MolBio, c1992, c199x, c19xx, TR 90/148, macromolecules,
TR90/148, TR148, 148 inductive inference, II, DNA, bioinformatics, DPA,
dynamic programming algorithm, mutual information, ML, string, sequence,
comparison, alignment, minimum message length encoding, MML, FSM, FSA,
finite state model, analysis, minimum description length, MDL, methods,
Hidden Markov model, HMM, homology, similarity, LCS, LCSS, significance,
evolutionary, edit distance, sequence, r-theory, linear, gap, indel, insert,
delete, Algorithm, Time, Speed, JME, AAAI, Bayes, Bayesian, CSWallace, CSW
%O An extended abstract titled:
Inductive inference over macro-molecules
in joint sessions at AAAI Symposium, Stanford MAR 1990
on (i) Artificial Intelligence and Molecular Biology, p5-9,
& (ii) Theory and Application of Minimal-Length Encoding, p50-54,
also an early version in Technical Report 90/148,
Dept. Comp. Sci., Monash U., Australia 3168.
%X MML encoding is a technique of inductive inference with theoretical and
practical advantages. It allows the posterior odds-ratio of two theories
or hypotheses to be calculated. Here it is applied to the problem of
aligning or relating two strings, in particular biological macro-molecules.
We compare the r-theory, that the strings are related, with the null-theory,
that they are not related. If they are related the probabilities of the
various alignments can be calculated. This is done for the one-, three-
and five-state models of relation or mutation. These correspond to linear
and piecewise linear cost functions on runs of indels. We describe how
to estimate the parameters of a model. The validity of a model is itself
a hypothesis and can be tested objectively. This is done on real DNA
and on artificial data. The tests on artificial data indicate limits on
what can be inferred in various situations. The tests on real DNA support
either the three- or the five-state models over the one-state model.
Finally, a fast, approximate minimum message length string comparison
algorithm is described.
-- [doi:10.1007/BF00160262]['07].
[reprint] and software,
See C. S. Wallace & D.M Boulton
An information measure for classification.
CompJ 11(2) 185-194 Aug '68 (appendix)
for the derivation of the coding scheme for multi-state data.
See also (i) Bishop & Thompson
(ii) Thorne, Kishino & Felsenstein, and
[AIMB](.ps),
[Alignment].
%A L. Allison
%A C. S. Wallace
%A C. N. Yee
%T When is a string like a string?
%J Int. Symposium on Artificial Intelligence and Mathematics
%W Ft. Lauderdale, Florida, USA
%M JAN
%D 1990
%K LAllison, CSW, CSWallace, Monash, conf, inductive inference, II, homology,
alignment, LCS, edit distance, string, sequence, comparison, similarity,
r-theory, macro-molecule, MolBio, DNA, uncertainty, pattern matching, MML,
minimum message length encoding, AIM AIM90, Hidden Markov model, HMM,
c1990, c199x, c19xx, bioinformatics
%X [more],
[html],
[.ps](.ps)
also see [TR90/148](html)
and [TR90/148](.ps).
%A L. Allison
%A C. N. Yee
%T Minimum message length encoding and the comparison of macromolecules
%J Bulletin of Mathematical Biology
%V 52
%N 3
%M MAY
%D 1990
%P 431-453
%O TR 89/126 Computer Science, Monash University, MAY '89
%K LAllison, Monash, jrnl, minimum message length encoding, MML, c1990, c199x,
c19xx, MDL, ML, inductive inference, II, minimum description length, DNA,
approximate, alignment, similarity, homology, LCS, LCSS, pattern matching,
string, sequence, comparison, Bayesian, Hidden Markov model, HMM,
mutual information, MolBio, bioinformatics, BMB, TR 89/126, 89 126, TR89/126
%X "A method of inductive inference known as minimum message length encoding is
applied to string comparison in molecular biology. The question of whether or
not two strings are related and, if so, of how they are related and the
problem of finding a good theory of string mutation are treated as inductive
inference problems. The method allows the posterior odds-ratio of two string
alignments or of two models of string mutation to be computed. The
connection between models of mutation and existing string alignment
algorithms is made explicit. A fast minimum message length alignment
algorithm is also described."
[more],
[doi:10.1007/BF02458580]['06].
%A L. Allison
%A T. I. Dix
%T A bit-string longest-common-subsequence algorithm
%J IPL
%V 23
%M DEC
%D 1986
%P 305-310
%K LAllison, TIDix, Monash, UWA, jrnl, MolBio, LCS, LCSS, c1986, c198x, c19xx,
fast, algorithm, bits string, bit vector, DPA, dynamic programming algorithm,
similarity, homology, bioinformatics, IPL, sequence, approximate, match,
matching, strings, distance, comparison, alignment, practical, speedup,
speed
%X "A longest-common-subsequence algorithm is described which operates in terms
of bit or bit-string operations. It offers a speedup of the order of the
word-length on a conventional computer."
Speedup is ~ wordlength (eg. a factor of 32 or 64), time is O(n^2/wordlength).
[more]+source code,
[HTML],
[.ps],
[doi:10.1016/0020-0190(86)90091-8]['07].